New Cell-Based Technology by Cytonus Aims to Revolutionize the Fight against Cancer and Inflammatory Diseases
Cytonus Therapeutics Inc. announced today that it has developed Cargocytes™ a first-of-its-kind, controllable, cell-based platform technology for delivery of biologics.
Cargocytes are engineered allogenic cell lines that can carry a variety of payloads like small molecule compounds, gene editing therapies, therapeutic RNAs, and powerful biologics such as immune modulating cytokines, antibodies and oncolytic viruses.
“Our technology revolutionizes the ability of cells to transport vital therapeutic payloads to targeted tissues in a safe, controllable, predictable and precise manner,” said Remo Moomiaie-Qajar, M.D., president and CEO of Cytonus. “We believe our Cargocytes have many structural and functional attributes making them the most versatile and capable cell-based drug delivery platform. Our different approach is well suited to address some of the most difficult to treat cancers and expands the possibilities of using various payloads to influence the immune system for many medical applications.”
Adoptive Cellular Therapies (ACTs), such as Tumor Infiltrating Lymphocytes (TILs) and T cells expressing Chimeric Antigen Receptors (CARs), are currently being tested and used to treat blood cancers, but do not work well on solid tumors. They are also hindered by the need for a specific antigen target, long development times, adverse patient reactions, rapid degradation and a complex manufacturing process.